{"id":7196,"date":"2025-09-16T21:07:35","date_gmt":"2025-09-16T21:07:35","guid":{"rendered":"https:\/\/pandapeptides.com\/?post_type=product&#038;p=7196"},"modified":"2026-04-09T10:30:42","modified_gmt":"2026-04-09T17:30:42","slug":"glp-g3","status":"publish","type":"product","link":"https:\/\/pandapeptides.com\/es\/producto\/glp-g3\/","title":{"rendered":"GLP-G3"},"content":{"rendered":"<div class=\"pp-answer-block\" style=\"background:linear-gradient(135deg,rgba(0,229,255,0.06) 0%,rgba(0,229,255,0.02) 100%);border-left:3px solid #00e5ff;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:24px\">\n<p style=\"color:#a1a1aa;font-size:15px;line-height:1.65;margin:0\"><strong style=\"color:#00e5ff\">Research Summary:<\/strong> R (GLP-G3) is a triple GIP\/GLP-1\/glucagon receptor agonist (LY3437943). CAS 2381089-83-2. Single alpha-helical peptide with engineered multi-receptor selectivity; C20 fatty diacid for extended activity. <em style=\"color:#71717a\">Research peptide only.<\/em><\/p>\n<\/div>\n<h2>GLP-G3<\/h2>\n<p><strong>Triple Agonist (GIP\/GLP-1\/Glucagon) \u2014 For Research Use Only<\/strong><\/p>\n<div style=\"background:#18181b;border-radius:12px;padding:20px 24px;margin:20px 0 28px\">\n<p style=\"color:#a1a1aa;font-size:15px;line-height:1.7;margin:0\">GLP-G3 is a triple incretin receptor agonist engaging GLP-1, GIP, and glucagon (GCGR) receptors simultaneously. CAS Registry Number: 2381089-83-2. Molecular weight: ~4,632.28 Da. Features a single alpha-helical peptide structure with engineered selectivity across all three receptor types. Research compound only.<\/p>\n<\/div>\n<h3>Product Details<\/h3>\n<ul>\n<li><strong>Compound:<\/strong> GLP-G3<\/li>\n<li><strong>Classification:<\/strong> Triple incretin receptor agonist<\/li>\n<li><strong>Pureza:<\/strong> &gt;99%<\/li>\n<li><strong>Form:<\/strong> Lyophilized powder<\/li>\n<p>mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg<\/li>\n<\/ul>\n<h3>Research Studies<\/h3>\n<p><em>(for educational purposes only)<\/em><\/p>\n<h4>Triple Receptor Agonism: GLP-1\/GIP\/GCGR Mechanism<\/h4>\n<p><strong>Source:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36070752\/\">PubMed PMID: 36070752<\/a><\/p>\n<p><strong>Summary:<\/strong> This study characterized GLP-G3 as a single-molecule triple agonist in receptor binding and cell-based signaling assays, demonstrating simultaneous engagement of GLP-1R, GIPR, and glucagon receptor with distinct potency ratios. Preclinical models examined the pharmacological consequences of concurrent activation of all three receptor systems.<\/p>\n<h4>Glucagon Receptor Signaling and Hepatic Energy Metabolism<\/h4>\n<p><strong>Source:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25365075\/\">PubMed PMID: 25365075<\/a><\/p>\n<p><strong>Summary:<\/strong> This review examined glucagon receptor (GCGR) pharmacology, characterizing G\u03b1s-coupled cAMP signaling in hepatocytes and its downstream effects on glycogenolysis, gluconeogenesis, and fatty acid oxidation pathways in cell and animal models. Research relevant to understanding the glucagon component of multi-receptor agonists.<\/p>\n<div class=\"pp-research-faq\" style=\"margin-top:40px\">\n<div style=\"margin-top:30px;margin-bottom:30px;padding:16px 24px;background:#18181b;border-radius:10px\">\n<p style=\"margin:0;color:#a1a1aa;font-size:14px\">\ud83d\udcda <a href=\"\/es\/research\/glp-g3\/\" style=\"color:#00e5ff;text-decoration:none;font-weight:600\">View Published Research on GLP-G3 \u2192<\/a><\/p>\n<p style=\"margin:6px 0 0 0;color:#52525b;font-size:12px\">Peer-reviewed citations from PubMed \u2014 for educational purposes only<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Triple GLP-1\/GIP\/glucagon receptor agonist \u00b7 >99% purity \u00b7 Janoshik verified \u00b7 Lyophilized powder<\/p>","protected":false},"featured_media":8059,"template":"","meta":[],"product_brand":[],"product_cat":[188],"product_tag":[150],"class_list":{"0":"post-7196","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-glp-receptor-agonists","7":"product_tag-badge-popular","9":"first","10":"instock","11":"taxable","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"_links":{"self":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product\/7196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/media\/8059"}],"wp:attachment":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/media?parent=7196"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_brand?post=7196"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_cat?post=7196"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_tag?post=7196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}