{"id":7278,"date":"2026-01-26T09:01:53","date_gmt":"2026-01-26T09:01:53","guid":{"rendered":"http:\/\/pandapeptides.com\/product\/semaglutide\/"},"modified":"2026-04-12T23:19:42","modified_gmt":"2026-04-13T06:19:42","slug":"glp-1-s","status":"publish","type":"product","link":"https:\/\/pandapeptides.com\/es\/producto\/glp-1-s\/","title":{"rendered":"GLP-1S"},"content":{"rendered":"<div class=\"pp-answer-block\" style=\"background:linear-gradient(135deg,rgba(0,229,255,0.06) 0%,rgba(0,229,255,0.02) 100%);border-left:3px solid #00e5ff;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:24px\">\n<p style=\"color:#a1a1aa;font-size:15px;line-height:1.65;margin:0\"><strong style=\"color:#00e5ff\">Research Summary:<\/strong> S (GLP-1 S) is a selective GLP-1 receptor agonist with 94% homology to native GLP-1. CAS 910463-68-2. Features Aib8 substitution for DPP-4 resistance; C18 fatty diacid enables extended half-life via non-covalent albumin binding. <em style=\"color:#71717a\">Research peptide only.<\/em><\/p>\n<\/div>\n<h2>GLP-1 S<\/h2>\n<p><strong>GLP-1 Receptor Agonist \u2014 For Research Use Only<\/strong><\/p>\n<div style=\"background:#18181b;border-radius:12px;padding:20px 24px;margin:20px 0 28px\">\n<p style=\"color:#a1a1aa;font-size:15px;line-height:1.7;margin:0\">GLP-1 S is a synthetic GLP-1 receptor agonist with 94% structural homology to native human GLP-1(7-37). CAS Registry Number: 910463-68-2. Molecular weight: ~4,113.58 Da. Features a C-18 fatty di-acid chain conjugated at position 26 (Lys26) enabling non-covalent albumin binding for extended pharmacokinetic half-life. Research compound only.<\/p>\n<\/div>\n<h3>Product Details<\/h3>\n<ul>\n<li><strong>Compound:<\/strong> GLP-1 S<\/li>\n<li><strong>Classification:<\/strong> GLP-1 receptor agonist<\/li>\n<li><strong>Pureza:<\/strong> &gt;99%<\/li>\n<li><strong>Form:<\/strong> Lyophilized powder<\/li>\n<p>mg, 10mg<\/li>\n<\/ul>\n<h3>Research Studies<\/h3>\n<p><em>(for educational purposes only)<\/em><\/p>\n<h4>GLP-1 Receptor Signal Transduction<\/h4>\n<p><strong>Source:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23684623\/\">PubMed PMID: 23684623<\/a><\/p>\n<p><strong>Summary:<\/strong> This review characterized GLP-1 receptor pharmacology, examining G\u03b1s-coupled cAMP\/PKA signaling, \u03b2-arrestin recruitment, and downstream Epac2-mediated pathways in pancreatic beta-cell models and neuronal cell lines.<\/p>\n<h4>Fatty Acid Acylation and Albumin Binding Pharmacokinetics<\/h4>\n<p><strong>Source:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26308095\/\">PubMed PMID: 26308095<\/a><\/p>\n<p><strong>Summary:<\/strong> This medicinal chemistry study described the design and structure-activity relationships of GLP-1 analogs with C-18 fatty diacid modifications. Research characterized how the acyl chain length, linker chemistry, and attachment position influence albumin binding affinity and proteolytic stability in vitro.<\/p>\n<div class=\"pp-research-faq\" style=\"margin-top:40px\">\n<div style=\"margin-top:30px;margin-bottom:30px;padding:16px 24px;background:#18181b;border-radius:10px\">\n<p style=\"margin:0;color:#a1a1aa;font-size:14px\">\ud83d\udcda <a href=\"\/es\/research\/glp-1-s\/\" style=\"color:#00e5ff;text-decoration:none;font-weight:600\">View Published Research on GLP-1 S \u2192<\/a><\/p>\n<p style=\"margin:6px 0 0 0;color:#52525b;font-size:12px\">Peer-reviewed citations from PubMed \u2014 for educational purposes only<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>GLP-1 receptor agonist \u00b7 31-amino acid peptide \u00b7 >99% purity \u00b7 Janoshik verified \u00b7 Lyophilized powder<\/p>","protected":false},"featured_media":8053,"template":"","meta":[],"product_brand":[],"product_cat":[188],"product_tag":[],"class_list":{"0":"post-7278","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-glp-receptor-agonists","8":"first","9":"instock","10":"sale","11":"taxable","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"_links":{"self":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product\/7278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/media\/8053"}],"wp:attachment":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/media?parent=7278"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_brand?post=7278"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_cat?post=7278"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_tag?post=7278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}