{"id":7307,"date":"2026-01-26T09:18:49","date_gmt":"2026-01-26T09:18:49","guid":{"rendered":"http:\/\/pandapeptides.com\/product\/hmg-human-menopausal-gonadotropin\/"},"modified":"2026-04-11T09:43:45","modified_gmt":"2026-04-11T16:43:45","slug":"hmg","status":"publish","type":"product","link":"https:\/\/pandapeptides.com\/es\/producto\/hmg\/","title":{"rendered":"HMG 75IU"},"content":{"rendered":"<div style=\"background:#18181b;border-radius:10px;padding:20px 24px;margin-bottom:30px\">\n<p style=\"color:#a1a1aa;font-size:15px;line-height:1.7;margin:0\"><strong style=\"color:#fafafa\">HMG 75IU<\/strong> is a urinary-derived glycoprotein preparation (CAS 9002-68-0) containing two heterodimeric glycoprotein components that share a common \u03b1-subunit. Standardized to 75 IU per vial. Supplied as lyophilized powder, third-party tested by Janoshik Analytical. <em style=\"color:#71717a;font-size:13px\">Research compound \u2014 for laboratory use only.<\/em><\/p>\n<\/div>\n<h2>HMG 75IU<\/h2>\n<p><strong>Glycoprotein Research Preparation \u2014 For Research Use Only<\/strong><\/p>\n<div style=\"background:#18181b;border-radius:10px;padding:20px 24px;margin-bottom:30px\">\n<p style=\"color:#a1a1aa;font-size:15px;line-height:1.7;margin:0\"><strong style=\"color:#fafafa\">HMG<\/strong> (CAS 9002-68-0) is a preparation of urinary-derived glycoproteins consisting of two heterodimeric components. Both components share a common 92-amino-acid \u03b1-subunit (~14.5 kDa protein core) and differ by their unique \u03b2-subunits of 111 and 121 amino acids, respectively. The \u03b1-subunit contains two N-linked glycosylation sites (Asn-52, Asn-78), contributing to the characteristic heterogeneity observed in electrophoretic and chromatographic analyses. <em style=\"color:#71717a;font-size:13px\">Research compound \u2014 for laboratory use only.<\/em><\/p>\n<\/div>\n<h3>Product Details<\/h3>\n<ul>\n<li><strong>Compound:<\/strong> HMG (Urinary Glycoprotein Preparation)<\/li>\n<li><strong>CAS:<\/strong> 9002-68-0<\/li>\n<li><strong>Components:<\/strong> Two heterodimeric glycoproteins with shared \u03b1-subunit<\/li>\n<li><strong>\u03b1-Subunit:<\/strong> 92 amino acids, ~14.5 kDa (protein core), two N-glycosylation sites<\/li>\n<li><strong>\u03b2-Subunits:<\/strong> 111 aa (~15.5 kDa) and 121 aa (~16.7 kDa), each with 1\u20132 N-glycosylation sites<\/li>\n<li><strong>Native MW:<\/strong> ~30\u201338 kDa per heterodimer (glycosylation-dependent)<\/li>\n<li><strong>Potency:<\/strong> 75 IU (standardized bioassay)<\/li>\n<li><strong>Form:<\/strong> Lyophilized powder (white to off-white)<\/li>\n<li><strong>Solubility:<\/strong> Soluble in aqueous buffers<\/li>\n<li><strong>Testing:<\/strong> Third-party verified by <a href=\"\/es\/certificates-of-analysis\/\">Janoshik Analytical \u2192 View COA<\/a><\/li>\n<li><strong>Storage:<\/strong> 2\u20138\u00b0C desiccated, protect from light.<\/li>\n<\/ul>\n<h3>Research Studies<\/h3>\n<h4>Structural Characterization<\/h4>\n<div style=\"background:#18181b;border-radius:10px;padding:16px 20px;margin:12px 0 20px\">\n<p style=\"color:#a1a1aa;font-size:14px;line-height:1.6;margin:0\">HMG preparations consist of non-covalently associated \u03b1\/\u03b2 heterodimers. The \u03b1-subunit is encoded by a single gene (chromosome 6q21.1-23) and is structurally conserved across both glycoprotein components. It features a cystine knot motif formed by three intramolecular disulfide bonds, a structural element common to the cystine knot growth factor superfamily. The distinct \u03b2-subunits each contribute additional disulfide bonds (six in the 111-aa subunit, six in the 121-aa subunit), yielding the characteristic tightly folded tertiary structure.<\/p>\n<\/div>\n<h4>Physicochemical Properties<\/h4>\n<div style=\"background:#18181b;border-radius:10px;padding:16px 20px;margin:12px 0 20px\">\n<p style=\"color:#a1a1aa;font-size:14px;line-height:1.6;margin:0\">The isoelectric point of HMG glycoprotein components ranges from pH 3.5\u20135.5, reflecting extensive sialylation of the N-linked oligosaccharide chains. Charge heterogeneity arises primarily from variable terminal sialic acid residues. The preparations can be resolved by isoelectric focusing into multiple glycoforms, a property used in quality control characterization. The lyophilized form demonstrates excellent long-term stability when stored desiccated at 2\u20138\u00b0C.<\/p>\n<\/div>\n<div style=\"margin-top:30px;margin-bottom:30px;padding:16px 24px;background:#18181b;border-radius:10px;border:1px solid rgba(255,255,255,0.06)\">\n<p style=\"margin:0;color:#a1a1aa;font-size:14px\">\ud83d\udcda <a href=\"\/es\/research\/hmg\/\" style=\"color:#00e5ff;text-decoration:none;font-weight:600\">View Published Research on HMG \u2192<\/a><\/p>\n<p style=\"margin:6px 0 0 0;color:#52525b;font-size:12px\">Peer-reviewed citations from PubMed \u2014 for educational purposes only<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Biological research preparation \u00b7 Janoshik verified \u00b7 Lyophilized powder<\/p>","protected":false},"featured_media":8065,"template":"","meta":[],"product_brand":[],"product_cat":[189],"product_tag":[],"class_list":{"0":"post-7307","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-growth-hormone-peptides","8":"first","9":"instock","10":"taxable","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product\/7307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/media\/8065"}],"wp:attachment":[{"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/media?parent=7307"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_brand?post=7307"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_cat?post=7307"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pandapeptides.com\/es\/wp-json\/wp\/v2\/product_tag?post=7307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}