HGH 191AA is a recombinant 191-amino acid polypeptide. CAS 12629-01-5. Molecular weight approximately 22,124 Da. Supplied as a lyophilized powder, ≥95% purity. Compuesto para investigación — not for human use.
Especificaciones del compuesto
Detalles del producto
- Compuesto: HGH 191AA
- CAS: 12629-01-5
- Molecular Weight: ~22,124 Da
- Sequence Length: 191 amino acids
- Pureza: ≥95% (Verificado por Janoshik)
- Forma: Polvo liofilizado
- Size: 15IU per vial
- Storage: -20°C, protect from light
- Pruebas: Ver COA (Verificado por Janoshik) →
Structural Characterization
HGH 191AA (somatotropin, somatropin) is a single-chain recombinant polypeptide comprising all 191 amino acid residues in the native somatotropin sequence. The tertiary structure adopts a characteristic four-helix bundle topology stabilized by two intramolecular disulfide bridges (Cys-53↔Cys-165, Cys-182↔Cys-189).
- Molecular Formula: C₉₉₀H₁₅₂₉N₂₆₃O₂₉₉S₇
- Isoelectric Point (pI): ~5.27
- UV Absorption: λmax 280 nm (Trp/Tyr chromophores)
- Extinction Coefficient: ~18,890 M⁻¹cm⁻¹ at 280 nm
Physicochemical Properties
- Appearance: White to off-white lyophilized cake
- Solubility: Freely soluble in aqueous buffers (pH 7.0–8.0); limited solubility below pH 4.5
- Thermal Stability: Lyophilized form stable at -20°C (≥24 months); aliquots stable at 2–8°C
- Electrophoresis: Single band ~22 kDa under reducing SDS-PAGE
