5-Amino-1MQ is a small molecule inhibitor (CAS 42464-85-9) of nicotinamide N-methyltransferase (NNMT), molecular weight 193.2 Da. NNMT methylates nicotinamide, affecting NAD+ salvage pathways. Research investigates its effects on cellular energy metabolism and adipocyte function in experimental models. Research compound — for laboratory use only.
Compound Specifications
Product Details
- Compound: 5-Amino-1MQ (5-Amino-1-Methylquinolinium)
- Purity: >99%
- Form: Powder
- Sizes: 5mg
- Testing: View COA (Verified by Janoshik) →
Research Studies
(for educational purposes only)
5-Amino-1MQ as a selective NNMT inhibitor
Source: PMC5826726
Summary: This study characterized 5-Amino-1MQ as a nicotinamide N-methyltransferase (NNMT) inhibitor in adipocyte cell models, examining effects on intracellular NAD+ levels and lipogenesis.
NNMT inhibition in diet-induced metabolic regulation models
Source: PMC8337113
Summary: This research investigated 5-Amino-1MQ in diet-induced obese mice, measuring body weight, adipose tissue mass, and adipocyte size changes over an 11-day study period.