KPV is a C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte stimulating hormone (α-MSH), molecular weight 342.4 Da. Unlike full α-MSH, KPV lacks melanocortin receptor binding activity. Research focuses on its anti-inflammatory signaling mechanisms independent of MC1R activation. Research compound — for laboratory use only.
Compound Specifications
Product Details
- Compound: KPV (Lys-Pro-Val)
- Purity: >99%
- Form: Lyophilized powder
- Sizes: 10mg
- Testing: View COA (Verified by Janoshik) →
Research Studies
(for educational purposes only)
KPV and melanocortin receptor activation
Source: Research Review
Summary: This review examined KPV as a tripeptide fragment derived from alpha-melanocyte stimulating hormone, investigating its interactions with melanocortin receptors (MC1R and MC3R) in immune cell models.
Alpha-MSH derived peptides in inflammatory models
Source: Published research literature
Summary: Research has examined KPV and related alpha-MSH fragments in mucosal barrier function models animal models, investigating effects on NF-κB pathway activation and cytokine production.