Semax Research & Janoshik COA

Reviewed by: Panda Peptides Research Team| Last updated: July 28, 2026|For laboratory reference only

How to read this Semax research page

Use this page as a map of published laboratory literature. The cited papers examine Semax in animal, cell, transcriptomic, proteomic, and artificial-membrane model systems. They do not establish product claims or human-use guidance.

Compound identity: Semax is identified in the cited literature as ACTH(4–7)PGP, a synthetic regulatory peptide.
Evidence map: each section names the experimental model and links directly to its PubMed record.
Documentation path: compare the Semax peptide product page, COA hub, research framework, and related Selank research page.

Panda Peptides products are for research use only. No dosing, administration, reconstitution, treatment, or human-use guidance is provided.

Research Library

Published research references for Semax — research reference only, not medical guidance

Semax and Transcriptome-Level Signaling

A genome-wide rat-brain study examined how Semax affected expression of genes related to immune and vascular signaling after focal ischemia-reperfusion. The paper is useful as a transcriptomic reference for Semax research, not as guidance for use.

Vanyushkina AA et al. “The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis.” BMC Genomics. 2014. PubMed

Semax and Protein Expression Profiling

A proteomics-focused rat study evaluated brain protein-expression changes associated with ACTH(4-7)PGP, also known as Semax, in an ischemia-reperfusion research model. This provides a reference point for molecular-pathway evaluation.

Medvedeva EV et al. “Brain Protein Expression Profile Confirms the Protective Effect of the ACTH((4-7))PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion.” Int J Mol Sci. 2021. PubMed

Semax and Copper/Aβ Model Systems

Recent in vitro work examined Semax as a copper-chelating peptide in artificial membrane and amyloid-beta model systems. The study is relevant for coordination chemistry and model-system research around Semax.

Tsvetkov PO et al. “Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models.” ACS Chem Neurosci. 2022. PubMed

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Documentation note: Use this page to review published literature references alongside Panda product specifications and batch COA links. Panda Peptides products are sold for research, laboratory, or analytical purposes only and are not for human or veterinary use.

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Panda Peptides Research Team

Research content review focused on published literature references, source quality, and documentation clarity.

Editorial Review

Reviewed by Elizabeth D. and James S. — Panda Peptides Research Team.

Last reviewed: August 2026.

This content summarizes published laboratory literature for research-reference purposes only. Products referenced by Panda Peptides are sold strictly for controlled laboratory, analytical, or reference use and are not consumer products.

Semax — Published Research

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