IGF-1 LR3 is an 83-amino acid synthetic peptide analog. CAS 946870-92-4. Molecular weight approximately 9111 Da. Supplied as a lyophilized powder, ≥98% purity by HPLC. Research compound — not for human use.
Compound Specifications
Product Details
- Compound: IGF-1 LR3
- CAS: 946870-92-4
- Molecular Weight: ~9111 Da
- Sequence Length: 83 amino acids
- Purity: ≥98% (Janoshik verified, HPLC)
- Form: Lyophilized powder
- Storage: -20°C desiccated
- Testing: View COA (Verified by ILS Laboratories) →
mg
Structural Characterization
IGF-1 LR3 is a single-chain 83-amino acid peptide featuring a 13-residue N-terminal extension and an Arg³ substitution relative to the native 70-residue IGF-1 sequence. The molecule contains three intramolecular disulfide bonds (Cys–Cys linkages), which constrain the peptide into a compact tertiary fold characteristic of the insulin superfamily.
- Peptide Class: Extended single-chain polypeptide
- Disulfide Bonds: Three intramolecular Cys–Cys bridges
- Key Modification: Arg³ substitution + 13-residue N-terminal extension
- Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
- Appearance: White to off-white lyophilized powder
Physicochemical Properties
- Solubility: Soluble in dilute acetic acid (0.1 M) and aqueous buffers at mildly acidic pH
- Isoelectric Point: ~8.4 (basic character from Arg/Lys content)
- UV Absorption: Aromatic residue signal from Tyr and Phe chromophores at 275–280 nm
- Stability: Lyophilized form stable at -20°C
- Analytical Methods: HPLC (purity), mass spectrometry (identity confirmation)